The dystopian survival saga escaped from Sunday's 21st annual extravaganza with the most golden popcorn-shaped trophies, including best fight for the film's final three-way battle and best on-screen transformation for Elizabeth Banks' over-the-top futuristic makeover. "Hunger Games" stars Jennifer Lawrence and Josh Hutcherson were also honored for best female and male performances.
"I've wanted to hold a golden popcorn since I was 4 years old," beamed Hutcherson.
With four wins out of eight nominations, "Hunger Games" didn't totally decimate the competition.
"God, Rob's not here, you guys. I don't really know what to do," said Stewart, who pretended to make out with herself.
"Bridesmaids" walked away with two awards, though their wins weren't televised. The cast of the naughty comedy won best gut-wrenching performance for the scene in which the ladies battled food poisoning, and Melissa McCarthy won the best comedic performance award.
The live, fan-favorite ceremony was hosted by bawdy actor-comedian Russell Brand.
"Tonight, I'm gonna keep my eyes peeled for my next wife," joked Brand. "Fasssssbender!"
In lieu of a wordy acceptance speech for his MTV Generation Award, the show's version of a lifetime achievement trophy, Johnny Depp performed with The Black Keys. Steven Tyler and Joe Perry presented the award to the 48-year-old "Pirates of the Caribbean" star, who accompanied The Black Keys on guitar for "Gold on the Ceiling" and "Lonely Boy."
"It's like the get-out-of-the-business award," said Depp.
Other winners Sunday included Shailene Woodley for breakthrough performance for "The Descendants," Jennifer Aniston as best on-screen dirtbag for "Horrible Bosses" and LMFAO's "Party Rock Anthem" from "21 Jump Street" for best music.
MTV is owned by Viacom Inc.
Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang